Commentary

Dear Mr. Morgenthaler,

Thank you for the “Health & Wellness Update.” I look forward to each issue, and the solid information it provides.

Praise for
Smart Publications
Health & Wellness Update

"For sometime now I have enjoyed reading Smart Publications. They are beautifully structured, well written and educational"

"Wealth of information for anyone that chooses alternative healing methods. It's an education in itself just to read one of these newsletters! Every time I get one I read it from cover to cover! Easy to understand and easy to decipher when looking for products. Well done! It's a joy to read."

Special Update on Fat-soluble Vitamin C

Fat-soluble versus water-soluble vitamins

Fat-soluble vitamin C

What else does vitamin C do?

• helps in the production of collagen and maintenance of healthy skin and blood vessels
  
  
• promotes the healing of scar tissue and fractures
  
  
• gives strength to blood vessels
  
  
• helps prevent and treat the common cold
  
  
• promotes healthy teeth and gums
  
  
• helps the body utilize iron and folic acid
  
  
• supports the thymus gland
  
  
• enhances T-cell production, increasing resistance to viral and bacterial infections, and some allergies
  
  
• helps increase interferon levels
  
  
• aids in the absorption of iron and the formation of red blood cells
  
  
• protects blood lipids from peroxidation2
  
  
• reduces the effects of some allergy-producing substances

Advantages of ascorbyl palmitate

• is a preventative against stomach cancer and colon cancer 3,4
  
  
• reduces the toxic effects of acetaminophen better than ascorbic acid 5, 6,7
  
  
• stimulates collagen synthesis at lower doses than ascorbic acid 8,9
  
  
• is a powerful free radical scavenger 10

References:

1. Higdon, R.N., Ph.D. The Bioavailability of Different Forms of Vitamin C. http://lpi.oregonstate.edu/
   ss01/bioavailability.html
   
   
2. Passwater, R.A., Ph.D. The New Supernutrition. Pocket Books, NY 1991
   
   
3. Shimpo K, Takahashi H, Tsuda H, Hibino T, Kawai K, Kimura C, Nagatsu T, Fujita K. Inhibition of hepatocellular carcinoma development and erythrocyte polyamine levels in ODS rats fed on 3'-methyl-4-dimethylaminoazobenzene by hemicalcium ascorbate, 2-O-octadecylascorbic acid, and ascorbyl palmitate. Cancer Detect Prev 1996;20(2):137-45.
   Abstract
   
   
4. Wargovich MJ, Harris C, Chen CD, Palmer C, Steele VE, Kelloff GJ. Growth kinetics and chemoprevention of aberrant crypts in the rat colon. J Cell Biochem Suppl 1992;16G:51-4
   Abstract
   
   
5. Mitra A, Kulkarni AP, Ravikumar VC, Bourcier DR. Effect of ascorbic acid esters on hepatic glutathione levels in mice treated with a hepatotoxic dose of acetaminophen. J Biochem Toxicol 1991 Summer;6(2):93-100.
   Abstract
   
   
6. Mitra A, Ravikumar VC, Bourn WM, Bourcier DR. Influence of ascorbic acid esters on acetaminophen-induced hepatotoxicity in mice. Toxicol Lett 1988 Nov;44(1-2):39-46
   Abstract
   
   
7. Jonker D, Lee VS, Hargreaves RJ, Lake BG. Comparison of the effects of ascorbyl palmitate and L-ascorbic acid on paracetamol-induced hepatotoxicity in the mouse. Toxicology 1988 Nov 30;52(3):287-95
   Abstract
   
   
8. Rosenblat G, Willey A, Zhu YN, Jonas A, Diegelmann RF, Neeman I, Graham MF. Palmitoyl ascorbate: selective augmentation of procollagen mRNA expression compared with L-ascorbate in human intestinal smooth muscle cells. J Cell Biochem 1999 Jun 1;73(3):312-20.
   Abstract
   
   
9. Rosenblat G, Perelman N, Katzir E, Gal-Or S, Jonas A, Nimni ME, Sorgente N, Neeman I. Acylated ascorbate stimulates collagen synthesis in cultured human foreskin fibroblasts at lower doses than does ascorbic acid. Connect Tissue Res 1998;37(3-4):303-11.
   Abstract
   
   
10. Perricone N, Nagy K, Horvath F, Dajko G, Uray I, Zs-Nagy I.
    The hydroxyl free radical reactions of ascorbyl palmitate as measured in various in vitro models. Biochem Biophys Res Commun 1999 Sep 7;262(3):661-5
    Abstract