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Glossary

Actinic keratosis: a precancerous skin growth that occurs on sun-damaged skin often looks like a red scaly patch and feels like "sandpaper".

Anti-angiogenics: stops blood vessels from developing, thus reduces blood flow to the cancer.

Apoptosis: fragmentation of a cell into membrane – bound particles.

Basal cell carcinoma: the most common form of skin cancer that involves cells in the lower part, or base, of the epidermis, the outer layer of skin.

BEC: a constant, specific mixture of glycoalkaloids extracted from plant materials that possesses good anticancer properties.

Benign: non-cancerous, a growth that does not spread to other parts of the body or damage normal tissue.

Biopsy: removal and examination of cells or tissue under a microscope to check for cancer.

Carcinoma: cancer that starts in tissues that cover or line organs in the body.

Cell lysis: destruction of a cell.

Chemotherapy: treatment with anti-cancer drugs.

Clinical trial: a research study done on human volunteers to decide if a new treatment is safe and effective.

Curaderm BEC5: a cream formulation that contains BEC and is used for non melanoma skin cancers.

Curettage: a surgical method of removing diseased tissue with a curette, a sharp-edged instrument.

Curette: a spoon-shaped surgical instrument with a sharp edge.

Dermatologist: a medical doctor who specializes in treatment of skin cancer and other skin diseases.

Dermatopathologist: a medical doctor, generally a dermatologist with subspecialty training in skin pathology.

Dermis: the layer of skin, located under the epidermis.

Electrodessication: a surgical method of drying-out tissue by touching it with a needle-like electrode that passes electric current into the tissue.

Epidermis: the outermost layer of skin, which is in contact with the environment, located above the dermis.

Erythema: reddening of the skin.

Ex Vivo: outside the living body.

Glycoalkaloid: a sugar combined with a nitrogen containing substance found in plants.

GCMS: Gas Liquid Mass Spectrometer, a device that can measure very small quantities of a substance.

Haematological: blood related substances.

Histological: analyses of minute structure, composition and function of tissues.

Independent investigators: investigators who have done studies separately and are uninfluenced by other investigators.

In Vivo: within the living body.

Keratolytic agents: substances that soften and dissolve or peel the horny layer of the outer layer of the skin.

Laser: an electronic device that focuses light into an intense beam used in skin cancer surgery to cut or destroy tissue.

Localized: cancer that is limited to one small area of the body and has not spread.

Lymph nodes: clusters of tissue found in the underarms, groin, neck, and other parts of the body that help fight disease. When cancer spreads, they often trap cancer cells.

Malignant: a cancerous growth that may destroy nearby normal tissue and spread to other parts of the body.

Matrix metalloproteinase inhibitors: substances that prevent tumour spread and prevent blood vessels from forming.

Melanocytes: skin cells that produce a pigment called melanin and can change into malignant melanoma.

Melanoma: cancer that occurs in melanocytes and is the most serious kind of skin cancer.

Metastasize: the spread of cancer cells from the original tumour to distant parts of the body.

Mohs micrographic surgery: a method of treating skin cancer in which the cancer and as little normal tissue as possible is removed.

Mole: a small usually dark skin growth that develops from pigment-producing cells called melanocytes.

Monoglycosides: substances that have one sugar attached to them.

Pathologist: a doctor who helps diagnose disease by examining cells and tissues under a microscope.

Pharmacodynamics: the study of the action and effects of drugs.

Pharmacokinetics: the action of drugs in the body over a period of time.

Photodynamic therapy: treatment with drugs that kill cancer cells when exposed to a special light.

Precancerous: a growth that may eventually turn malignant and become cancerous.

Protocol: an explicit, detailed plan of an experiment.

Published information: unbiased, independent reviewed information such as scientific research that is printed in medical journals and is in public domain.

Radiation therapy: treatment that uses x-rays and other sources of radiation to kill cancer cells.

Recur: cancer that returns after treatment to the same site or a new site in the body.

Solasonine & Solamargine: glycoalkaloids found in Solanaceous plants such as the eggplant. The glycoalkaloids possess good anticancer properties.

Squamous cell carcinoma: cancer that occurs in squamous cells, which are specialized cells near the skin surface that produce protective keratin.

Topical chemotherapy: treatment with anticancer drugs in a cream or solution applied to the skin over a period of time.

Triglycosides: substances that have three sugars attached to them.

Tumour: any abnormal growth of tissue that can be either benign (non-cancerous) or malignant (cancerous).

Ultraviolet radiation: invisible rays in sunlight that cause suntan, sunburn, premature skin ageing, and most cases of skin cancer.

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