- A
- A
- A
Syndrome X: The Secret to the Puzzle of Weight Control
Anti-Syndrome-X Nutritional Supplements
The nutrients reviewed in the following sections all play a critical role in maintaining proper insulin function and help to reverse Syndrome X.
Alpha lipoic acid (ALA) Improves Insulin Sensitivity and Much More
This sulfur-containing fatty acid, found in spinach and animal protein, has been shown to lower glucose levels by 10 to 30 percent and improve insulin function.10 ALA also has been used to positively prevent and treat diabetic nerve disease and reduce the incidence of cataracts in laboratory animals.11 ALA is also believed to reverse some of the fundamental signs of aging, according to a recently published animal study in which old rats that were given alpha-lipoic acid supplements had the same energy levels as young rats.12
Green Tea The Natural Starch Blocker Plus …
Studies confirm that tea catechins—potent antioxidants—are effective in suppressing increases of glucose and insulin concentrations in the blood. Since blood sugar tends to increase with age, this effect is an extremely important anti-aging benefit.13
Plus, tea polyphenols inhibit the activity of amylase, a starch-digesting enzyme found in saliva and in the intestines. Starch is broken down more slowly, and the rise in serum glucose is minimized, so that you don't crave sweets and other snack foods after eating a meal.14 Since insulin is our most fattening hormone and, with cortisol, our most pro-aging hormone, if you drink Green Tea or take its extract in the form of a nutritional supplement, you gain a wide range of benefits that accompany calorie and insulin control.
This "starch blocking" effect of green tea may be part of the reason Japanese people living in Japan can eat so much rice but remain thin. They have a tradition of drinking green tea before every meal.
The antioxidants in Green Tea also help reduce the oxidation of low-density lipoprotein (LDL) or "bad" cholesterol, a process that can lead to clogged arteries.15
Chromium Picolinate First Class Blood Sugar and Insulin Regulator
Nine out of 10 American diets fall short of this trace mineral, which is essential for the transfer of sugar from the bloodstream to muscle cells, thereby giving them the fuel they need to work. Chromium is involved in maintaining cholesterol and triglyceride levels, and it is also necessary for our muscles to function properly. Chromium picolinate is believed to be more effective than other chromium supplements tested because it transports chromium into the cells more efficiently.16
Chromium is believed to help build new muscle and act as a fat burner. When combined with an exercise program, chromium supplementation, even without the other synergistic supplements we suggest, has been shown to produce significant weight loss.17
Research suggests that chromium picolinate may help those with diabetes II and hypoglycemia.18 According to a study by U.S. Department of Agriculture researcher John Anderson, there is strong evidence that chromium picolinate may help to normalize glucose and insulin levels in diabetics. In this study, chromium was tested in 180 people in China with Type II (adult onset) diabetes. The scientists found that higher doses of chromium helped normalize glucose and insulin levels in the participants. "We've been doing chromium studies for 20 years and never saw anything this spectacular," said Anderson. "If you take people in the general population with slightly elevated blood sugar and give them chromium supplements, you'll see a drop in blood sugar in 80 to 90 percent of them."19
Salacia Reticulata Supports Healthy Blood Lipids
This herb has been traditionally used in Indian medicine to treat diabetes. It has potent antioxidant properties,20 and triglyceride - and LDL cholesterol-lowering effects that aid in weight loss. Salacia contains mangiferin, which enhances the body's sensitivity to insulin, and also contains inhibitors of sugar digestion and absorption.21
Banaba Effective in Supporting Healthy Body Weight
Banaba is a botanical extract that comes from the leaves of banaba trees and is traditionally used in the Philippines as an herbal medicine for diabetes. Corosolic acid, a triterpenoid in the leaves, acts as a glucose transport stimulator. It also appears to have strong antioxidant properties. Animal studies have shown it to be effective both for treating diabetes and obesity.22
Momordica A Powerful Pancreas Protector
Also called bitter gourd or bitter melon, Momordica is used as a vegetable in India. Its extract improves glucose metabolism, protects the pancreas, slows carbohydrate absorption, and decreases gluconeogenesis, which is the production of glucose in the liver from other foodstuffs. It has also been shown to improve insulin resistance,23 protect and regenerate insulin-producing pancreas cells,24 and lower both blood lipids and glucose.25
Coccinia Supports Normal Glucose Oxidation
Also called Ivy gourd, this Indian herb is related to bitter gourd and is used for similar purposes as Momordica. It decreases the liver's own production of blood sugar, and increases glucose oxidation in the liver.26
Vanadyl Sulfate The Other First Class Insulin and Blood Sugar Regulator
In 1980, this salt of the ultra-trace element vanadium was found to mimic almost all the known actions of insulin, driving sugar and amino acids into muscle or brain cells. Tests in patients with diabetes show that vanadyl sulfate can lower insulin levels and blood pressure, and improve or normalize blood glucose.27 Much of the research, so far, has been done on animals. But Dr. A.B. Goldfine and her colleagues at the Joslin Diabetes Center have found that oral vanadyl sulfate treatment resulted in improved insulin sensitivity in humans with adult-onset diabetes. Serum cholesterol levels as well were lowered in research participants.28
Editor's Note:
The natural health solutions described in this article are available through many on-line retailers including those listed below. By clicking these links you help support the important alternative health research we provide.
Visit www.amazon.com – a great way to find competitive deals on supplements offered by many different manufacturers.
Visit www.hfn-usa.com – when commitment to quality and freshness is important, this factory direct solution is preferred by many of our readers.
This article is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.
References
-
Reaven, G. Syndrome X.Clinical Diabetes. 1994; 3-4, 32-52.
-
Reaven, G. Syndrome X: 6 years later. J Int Med Suppl. 1994;736;13-22
-
McCarty MF. Enhancing central and peripheral insulin activity as a strategy for the treatment of endogenous depression. Med Hypotheses. 1994; 43 (4): 247-252.
-
Challem, Jack, Smith, Burt Berkson, M.D., Ph.D., Melissa Diane Smith. Syndrome X: The Complete Nutritional Program to Prevent and Reverse Insulin Resistance, 2000, John Wiley & Sons.
-
Dilman, V, Dean. W. The Neuroendocrine Theory of Aging and Degenerative Disease. Pensacola, FL:The Center for Bio-Gerontology, 1992.
-
The Burton Goldberg Group. Alternative Medicine pg. 764, Future Medicine Publishing, Inc., 1997, CA.
-
DesMaisons, Kathleen, Ph.D. Potatoes Not Prozac, pg. 31, Simon & Schuster, 1998, New York.
-
Everson SA, et al. Weight gain and the risk of developing insulin resistance syndrome. Diabetes Care. 1998;21(10):1643-1643.
-
Mooradian Ad, Thurman, JE. Glucotoxicity - potential mechanisms. Clinics in Geriatric Med. 1999; 15(2):255-262.
-
Jacob S, et al. The radical scavenger a-lipoic acid enhances insulin sensitivity in patients with NIDDM: a placebo-controlled trial. Presented Oxidants and Antioxidants in Biology, Santa Barbara, CA., 1997 Feb 26-Mar 1.
-
Nagamatsu M et al. Lipoic acid improves nerve blood low, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care, 18: 8,1995 Aug, 1160-7.
-
Hagen TM, Ingersoll RT, Lykkesfeldt J, et al., "(R)-a-lipoic acid supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate," FASEB JOURNAL, 1999.
-
Horigome, T., Kumar, R and Okamoto, K.: Brit J. Nutr., 60,275-285 (1988)
-
Kreydiyyeh SI et al. Tea extract inhibits intestinal absorption of glucose and sodium in rats. Comp Biochem Physiol C Pharmacol Toxico Endocrino 1994;108:359-65.
-
Luo, M., et al. "Inhibition of LDL oxidation by green tea extract." The Lancet 199, 349:360-361.
-
Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J et al. "Elevated intakes of supplemental chromium improve glucose and insulin individuals with Type 2 Diabetes." Diabetes 1997;46(11):1786-91.
-
Grant, K.E., et al. "Chromium and exercise training: Effect on obese women," Med Sci Sports Ex 29(8):992-998, 1997.
-
Evans, G.W. "The Effect of Chromium Picolinate on Insulin Controlled Parameters in Humans." International Journal of Biosocial Medical Research 11 no.2 (1989): 163-180.
-
Anderson, R.A.; et al. "Effects of Supplemental Chromium on Patients with Symptoms of Reactive Hypoglycemia." Metabolism: Clinical and Experimental 36 no. 4 (Apr, 1987): 351-355.
-
Yoshikawa M, Ninomiya K, Shimoda H, Nishida N, Matsuda H. "Hepatoprotective and antioxidative properties of Salacia reticulata: preventive effects of phenolic constituents on CCl4-induced liver injury in mice." Biol Pharm Bull 2002 Jan;25(1):72-6
-
Yoshikawa M, Morikawa T, Matsuda H, Tanabe G, Muraoka O. "Absolute Stereostructure of Potent alpha-Glucosidase Inhibitor, Salacinol, with Unique Thiosugar Sulfonium Sulfate Inner Salt Structure from Salacia reticulata." Bioorg Med Chem 2002 May;10(5):1547-54
-
Suzuki Y, Unno T, Ushitani M, Hayashi K, Kakuda T. "Antiobesity activity of extracts from Lagerstroemia speciosa L. leaves on female KK-Ay mice." J Nutr Sci Vitaminol (Tokyo) 1999 Dec;45(6):791-5
-
Miura T, Itoh C, Iwamoto N, Kato M, Kawai M, Park SR, Suzuki I. "Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice." J Nutr Sci Vitaminol (Tokyo) 2001 Oct;47(5):340-4
-
Ahmed I, Adeghate E, Sharma AK, Pallot DJ, Singh J. "Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat." Diabetes Res Clin Pract 1998 Jun;40(3):145-51
-
Ahmed I, Lakhani MS, Gillett M, John A, Raza H. "Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats." Diabetes Res Clin Pract 2001 Mar;51(3):155-61
-
Shibib BA, Khan LA, Rahman R. "Hypoglycaemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase." Biochem J 1993 May 15;292 ( Pt 1):267-70
-
Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism (United States) Sep 1996, 45 (9) p1130-5.
-
Goldfine, A.B.,D.C. Simonson, F.Folli, M.E. Patti, and C.R. Kahn. "Metabolic Effects of Sodium Metavanadate in Humans with Insulin Dependent and Non-Insulin Dependent Diabetes Mellitus in Vivo and in Vitro Studies." J ournal of Clinical Endocrinological Metabolism 80, no.11 (1995): 33111-20.
