Smart Publications

Clarifying the Complex World of Nutrition Science

  • Email this article
  • Print this article
  • A
  • A
  • A

Soy Isoflavones are Safe and Effective for Preventing Breast Cancer

by Jonathan V. Wright, M.D.

Soy Isoflavones are Safe and Effective for Preventing Breast Cancer

Soy isoflavones are phytoestrogens—naturally occurring estrogen-like compounds derived from plants. They are sold as a supplement for bone and heart health, and menopausal symptoms, and do not have the harmful side effects of some estrogens.

But some studies indicating that breast cancer cells in mice were stimulated by soy isoflavones cast a shadow on the supplement’s image. That image is about to change, thanks to several new studies.

According to results of the Osteoporosis Prevention Using Soy (OPUS) study published in the Journal of Nutrition, May, 2009, postmenopausal women who were given two different doses of soy isoflavones did not experience an increase in the density of breast tissue. Instead, there was a decrease in breast tissue density.

Since breast density is a general marker of breast cancer this is great news. The findings reassure users that soy isoflavones don’t act like hormone replacement medication on breast density.

The multi-site, double-blinded trial randomly assigned 406 postmenopausal women to a daily dose of 80 or 120 mg of isoflavones or a placebo for two years. According to the researchers, these doses are equivalent to the amounts of isoflavones provided in a daily serving of two to four cups of soymilk.

The average age of the 358 women who completed the trial was 55. At the start of the trial all the women had a similar body mass index (BMI), but the average breast density varied.

Over time, the change in breast density was significant, with breast density decreasing by 1.6% per year across all groups who took the soy supplements. The researchers concluded that the results offer some reassurance to those who have been concerned about adverse effects of soy supplementation on breast cell proliferation.1

Recent Studies

Two recent studies indicate that a high intake of soy during childhood and adolescence may reduce a woman’s risk of breast cancer later in life

The first one, published in the June ’09 issue of the American Journal of Clinical Nutrition, assessed the dietary intake of 73,223 Chinese women who participated in the Shanghai Women’s Health Study. It is a well-known fact that women who live in countries where soy is an integral part of the diet have a lower incidence of some types of cancer. And China happens to have the world's lowest incidence and mortality from breast cancer.

A seven-year follow-up documented 592 incidences of breast cancer. Adolescent intakes of soy foods were associated with a 43 percent reduction in premenopausal breast cancer risk, while high intakes of soy protein and isoflavones were associated with 59 and 56 percent reductions in the risk of breast cancer before menopause.2

A second study interviewed 597 American women of Chinese, Japanese, and Filipino descent who had breast cancer, and 966 healthy women between the ages of 20 and 55 about their adolescent and adult diets. Additionally, the mothers of 255 participants who were living in the U.S. were asked about their daughter’s early intake of soy.

When Asian women migrate to the United States, their breast cancer risk typically increases over several generations. But the study found that soy intake during childhood, adolescence, and adult life was associated with decreased breast cancer risk.

The researchers determined that women with the highest soy intake during childhood had a 58 percent lower risk of breast cancer as adults than the women with the lowest soy intake during childhood. High soy intake during adolescence and adulthood was associated with a 20 to 25% reduction.3

Conclusion

Soy isoflavones do not increase breast density, and women who consume a high amount of soy foods consistently during adolescence and adulthood have a substantially reduced risk of breast cancer. 

Editor's Note:

The natural health solutions described in these article are available through many on-line retailers including those listed below. By clicking these links you help support the important alternative health research we provide.

Visit NutriStand – The Nutrition Newsstand from the Supplement Man for Science-Based Nutritional Supplements!

Visit International Antiaging-Systems for hard to find therapies. They specialize in Tomorrow's Treatments Today™.

Visit www.amazon.com – a great way to find competitive deals on supplements offered by many different manufacturers.

Visit VitaE8 - The Ultimate Vitamin E – to learn more about the importance of full-spectrum vitamin E supplements.

These articles are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.

References

  1. Maskarinec, G., Verheus, M., Steinberg, F.M., Amato, P., Cramer, M.K., Lewis, R.D., Murray, M.J., Young, R.L., Wong, W.W. “Various doses of soy isoflavones do not modify mammographic density in postmenopausal women” Journal of Nutrition, May 2009, Volume 139, Pages 981-986. 

  2. Lee SA, Shu XO, Li H., Yang G., Cai H., Wen W., Ji BT, Gao J, Gao YT, Zheng W. “Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study,”American Journal of Clinical Nutrition, June 2009, Volume 89, Number 6, Pages 1920-1926. 

  3. Korde LA, Wu AH, Fears T, Nomura AM, West DW, Kolonel LN, Pike MC, Hoover RN, Ziegler RG. Childhood soy intake and breast cancer risk in Asian American women. Cancer Epidemiol Biomarkers Prev. 2009 Apr;18(4):1050-9. 

Related Articles

2 Comments

Haven’t you always heard that prevention is always better than cure? It would be something that the people would not understand until there arises a situation for each one of them. Only when it affects them or their loved ones they would react to it. EHR

ugg boots
tods outlet
jordan 6
coach factory outlet
ugg australia
ray bans
kevin durant shoes
canada goose jackets
adidas shoes
louis vuitton handbags
canada goose sale
canada goose jackets
ugg outlet
fitflops outlet
concords 11
uggs outlet
adidas running shoes
ugg boots
ugg outlet
coach outlet
oakley sunglasses wholesale
coco chanel
abercrombie store
ugg boots sale
burberry scarf
coach factory outlet
jordan retro
copy watches
hollister clothing store
mont blanc mountain
beats studio
louis vuitton outlet stores
gucci shoes
polo ralph lauren
michael kors outlet online sale
oakley sunglasses
coach outlet
oakley sunglasses cheap
cheap oakley sunglasses
true religion jeans
ghd hair strighteners
nike shoes
jordan 11s
timberland pro
moncler jackets
hollister clothing
christian louboutin sale
timberland outlet
fitflops
oakley sunglasses
cheap uggs
mont blanc pen
hollister clothing
louis vuitton handbags
coach factory outlet online
ugg boots
uggs outlet
gucci outlet
hollister
insanity workout
ugg australia
beats by dr dre
coach outlet store online
adidas outlet
burberry handbags
canada goose
burberry outlet online
louis vuitton handbags
fitflop footwear
fendi outlet
kobe shoes
rayban sunglasses
coach factory outlet
gucci belts
michael kors
marc by marc jacobs
cheap jerseys
kate spade
true religion
abercrombie
louis vuitton outlet
ugg boots on sale
lebron james shoes
ray ban sunglasses outlet
coach factory outlet
cheap timberland boots
adidas wings
ray ban outlet
michael kors outlet
fake watches
moncler outlet
retro 11
michael kors
white timberland boots
abercrombie
hollister
red bottom shoes
true religion outlet
burberry outlet online
burberry sale
ray ban glasses
polo ralph lauren
michael kors uk
ugg slippers
coach factory outlet online
jordan 13
guess outlet
michael kors outlet online
tory burch
cheap lululemon
jordan shoes
abercrombie and fitch
[url=http://www.louisvuitton.com]http://www.louisvuitton.com[/url]
chanel outlet online
canada goose
coach factory outlet
moncler
louis vuitton
nike outlet
timberland boots
ray ban wayfarer
coach factory
timberland uk
supra shoes
true religion jeans
louis vuitton outlet
abercrombie store
michael kors outlet online sale
michael kors outlet
tory burch outlet online
hollister clothing
adidas outlet store
timberland canada
tods shoes
true religion jeans
canada goose
ray ban sunglass
michael kors
michael kors
timberland outlet
cheap toms
polo outlet
jordan 8
canada goose outlet
burberry outlet
louis vuitton handbags
toms canada
uggs on sale
oakley sunglass
concord 11
burberry handbags
louis vuitton outlet
louis vuitton
celine outlet
burberry outlet online
louis vuitton
oakley sunglass
fitflop shoes
coach outlet store online
christian louboutin shoes
mont blanc pens
hollister clothing
toms shoes
abercrombie and fitch new york
coach outlet store online
louis vuitton outlet
jordan concords
cheap uggs
oakley sunglasses wholesale
louis vuitton outlet
kors outlet
gucci bags
hollister clothing store
louis vuitton outlet online
louis vuitton
christian louboutin outlet
canada goose jackets
timberland canada
discount oakley sunglasses
timberland boots
true religion outlet
red timberland boots
ray ban sunglasses
abercrombie outlet
belstaff
chi flat iron
christian louboutin
abercrombie
red bottoms
white timberland boots
uggs outlet
ugg boots
ugg boots
christian louboutin sale
jeremy scott adidas
air jordan 11
jordan 11
michael kors
ugg outlet
christian louboutin
toms outlet
burberry outlet online
jordan 11 gamma blue
jordan 11 low
lebron james shoes
polo ralph lauren
burberry handbags
burberry outlet
true religion sale
ugg boots sale
burberry outlet
louis vuitton handbags
beats headphones
ugg boots
ray ban wayfarer
jordan 4
true religion outlet
coach outlet
louis vuitton outlet
ray ban outlet
ugg boots outlet
ugg outlet
michael kors outlet online
gucci shoes
michael kors outlet
christian louboutin sale
uggs outlet
abercrombie
oakley outlet
abercrombie store
chanel handbags
cheap beats bydre
p90x workouts
michael kors handbags
abercrombie & fitch
timberland boots
louis vuitton
coach outlet store online
ralph lauren polo shirts
ralph lauren outlet
chanel online shop
toms
michael kors handbags
hollister jeans
oakley sunglasses outlet
coach outlet store online
coach factory outlet
coach outlet store online
michael kors outlet
christian louboutin outlet
chanel bags
ralph lauren outlet
moncler jackets
timberland uk
christian louboutin shoes
louis vuitton
abercrombie
lululemon
abercrombie & fitchfitch
tory burch shoes
canada goose outlet
jordan 11
coach outlet
tods shoes outlet
abercrombie
burberry scarf
true religion
coach outlet stores
kors outlet
timberland uk
yoga pants
imitation watches
toms shoes
hermes birkin
timberlands
black timberland boots
abercrombie and fitch
hollister clothing store
cheap nfl jerseys
uggs on sale
oakley sunglasses
coach outlet
ralph lauren outlet
coach factory outlet
cheap oakleys
christian louboutin
[url=http://www.louisvuitton.com]http://www.louisvuitton.com[/url]
oakley vault
louis vuitton handbags
ralph lauren
ugg outlet
gucci outlet
hollister co
christian louboutin outlet
burberry outlet online
gucci handbags
hollister kids
toms outlet
cheap nfl jerseys
hollister outlet
burberry
burberry scarf
cheap louis vuitton handbags
toms outlet
fitflops clearance
ugg outlet
timberland outlet
north face outlet
coach factory
michael kors outlet online
canada goose outlet
ray ban sunglasses
hogan shoes
toms shoes
cheap jerseys
mont blanc
red timberland boots
canada goose outlet
jordan retro 11
hollister kids
ugg outlet
marc jacobs
louis vuitton
burberry outlet
chanel handbags
burberry outlet
cheap uggs
ray bans
tory burch outlet online
oakley sunglasses wholesale
ugg australia
canada goose
ugg boots
abercrombie fitch
cheap jordans
mont blanc
michael kors handbags
ray ban aviators
jordan 11 columbia
louis vuitton outlet
chanel handbags
burberry bags
rolex watches outlet
dior handbags
burberry bags
ugg sale
kids uggs on sale
louis vuitton
ralph lauren uk
red christian louboutin
true religion
michael kors outlet online
ugg australia
burberry outlet
canada goose outlet
timberland
jordan 11
chanel outlet
ugg outlet
tory burch flats
burberry scarf
abercrombie kids
tory burch shoes
knockoff watches
uggs outlet
chanel bags
louis vuitton handbags
chanel bags
timberland earthkeepers
burberry outlet online
cheap nfl jerseys
michael kors outlet
tory burch handbags
rayban outlet
burberry sale
jordan 13
belstaff jackets
louis vuitton
canada goose
timberland uk
fitflops
jordan 11 low
christian louboutin sale
jordan 11 gamma blue
coach factory
christian louboutin outlet
uggs on sale
celine outlet
michael kors outlet online
the north face
timberland boots
prada outlet
true religion
michael kors handbags
burberry sale
canada goose outlet
tory burch outlet
polo ralph lauren home
canada goose jackets
chanel
michael kors outlet
true religion kids
canada goose jacket
gucci outlet
mont blanc pens
tory burch outlet online
michael kors outlet online
mont blanc legend
michael kors outlet
kobe bryant shoes
michael kors outlet online sale
rayban sunglass
jordan 4
uggs outlet
coach outlet
black timberland boots
canada goose
christian louboutin outlet
jordan 3
football jerseys
marc jacobs
coach factory outlet
oakley sunglasses wholesale
michael kors
ugg boots
ugg boots
tory burch outlet
michael kors outlet online
kate spade outlet
replica rolex watches
christian louboutin
abercrombie outlet
canada goose jackets
ugg boots
tory burch outlet online
ugg boots
toms promo code
oakley sunglasses
louis vuitton outlet stores
toms wedges
cheap jerseys
chanel outlet
red heels
retro jordans
uggs sale
hollister co
canada goose jackets
replica watches
louis vuitton handbags
bottega veneta outlet
uggs outlet
burberry bags
timberland earthkeepers
burberry outlet
coach outlet
uggs outlet
michael kors outlet
burberry handbags
tory burch outlet
canada goose jackets
ralph lauren outlet online
ugg outlet
louis vuitton outlet
burberry outlet
abercrombie
beats solo
rayban sunglasses
tory burch outlet
timberlands
michael kors outlet
tods sale
tods outlet store
michael kors outlet online
louis vuitton outlet
gucci outlet
michael kors
true religion sale
oakley sunglasses cheap
ugg sale
tory burch sale
burberry bags
ss2

Leave a Comment

Commenting is not available in this channel entry.