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Nourish Your Skin and Remove Wrinkles with Hyaluronic Acid and Collagen

Nourish Your Skin and Remove Wrinkles with Hyaluronic Acid and Collagen

Cosmeceuticals—a marriage between cosmetics and pharmaceuticals—is the fastest-growing segment of the natural personal care industry. And it’s no wonder. Because if you’re like most people over 40 you want to avoid or get rid of the crow’s feet around your eyes and the vertical lines above your lips.

One of the newest cosmeceuticals to hit the market is hyaluronic acid.

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What is hyaluronic acid?

Hyaluronic acid is a non-sulfated glycosaminoglycan distributed widely throughout the body in the connective, epithelial, and neural tissues. It is one of the chief components of the extracellular matrix and contributes significantly to cell proliferation and migration. The average person has roughly 15 grams of hyaluronic acid in their body, one third of which is lost and replaced each day.1

How does it work?

The surface layers of the skin are supported from below by columns of fibers made up mostly of collagen and elastin. This network of fibers forms the molecular sponge known as connective tissue.

Keeping Your Skin Hydrated—Hyaluronic Acid and Collagen

The spaces within this sponge are filled with a composition of water, protein complexes, and hyaluronic acid. This jelly-like complex transports essential nutrients from the bloodstream, via the capillaries in your skin. Hyaluronic acid attracts and holds water, which is what plumps your skin so that wrinkles and lines are less visible. 

With properties like that, it is clear that hyaluronic acid is vital to:

  • Curb premature wrinkling
  • Increase skin hydration
  • Keep skin moist and smooth
  • Boost skin elasticity
  • Enhance collagen synthesis
  • Nourish healthy skin cell growth
  • Promote firm skin tone
  • Support healthier joints

Searching for beauty in all the wrong places

In 2005, Americans spent more than $12.5 billion on cosmetic procedures that promise to help restore the dewy glow of youth. With baby boomers and more men looking for innovative ways to slow the aging process, it’s estimated that the medical-aesthetic economy—including device sales and doctors’ fees—will soon surpass $20 billion.

The problem is, Botox, chemical peels, and fillers are temporary quick fixes, expensive and not without risk. Botox is delivered in tiny, non-lethal doses of botulinum toxin, which interferes with nerve function for months at a time. In the end, it could very well cause permanent nerve damage. Injected fillers meant to plump up wrinkles and lines can result in infection, bruising, swelling, and pain.


And honestly—if you’ve been trying hard to eat a healthy diet, and supplement it with nutritional supplements why would you even consider injecting your face with chemicals?

Hyaluronic acid is a healthy alternative for fighting the effects of aging … and the good news is that it’s inexpensive, natural, and free of side effects.

“… it’s also important to replenish diminishing stores of hyaluronic acid, because HA is one of the skin’s most important components for hydration and moisture retention.”

Nourish your skin from the inside out

Slathering your skin with topical creams and ointments helps protect against the elements, but the best way to maintain moist, beautiful skin is to nourish it from the inside out. Drinking 8-10 glasses of purified water each day is important, but it’s also important to replenish diminishing stores of hyaluronic acid, because HA is one of the skin’s most important components for hydration and moisture retention. And without the proper levels of HA in the upper layers of the epidermis, your skin appears dull and wrinkled.

Can a hyaluronic acid supplement really help?

According to this theory, it can. We’re all exposed to free radicals through daily exposure to UV rays and environmental pollutants, which inevitably degrades and destroys hyaluronic acid. HA begins to decrease in your early 20s and this accelerates when you hit 40. (In fact, 50 year olds are estimated to have less than half the hyaluronic acid of people in their 20s.)4  There is a decrease in the amount of hyaluronic fluid and its synthesis, which in turn leads to a decrease in intra-cellular fluid. This results in skin that is drier and more vulnerable to damage.

The formation and maintenance of collagen, which is also vital to maintaining skin elasticity and tone, is affected. You begin to notice more crow’s feet and wrinkles because your skin loses its elasticity.

Luckily, you can enhance the amount and absorption of HA by taking an inexpensive, natural nutritional supplement. And the added bonus is that HA helps support healthy joints!

Facts about hyaluronic acid23

  • HA is a member of the family of molecules called glycosaminoglycans, which also includes chondroitin sulfate. It is an excellent lubricant in the body.
  • Hyaluronic acid is produced in the human body and is found in the tissues of all animals.
  • HA is also a major ingredient of the synovial fluid that lubricates and cushions joints. Without the appropriate levels of HA, the synovial fluid loses its ability to perform, which leaves the joints unprotected and the cartilage undernourished.
  • HA was isolated about sixty years ago from vitreous humor that fills the inner chamber of the eye.
  • Its name is derived from the Greek word for glass (hyalos), which accurately describes its transparent, glassy appearance.
  • In skin, HA, along with water and protein complexes, fills the spaces in connective tissue.
  • The nature of HA’s molecular structure makes it ideal for attracting and holding water.

Scientific studies

Although there are numerous studies on the injectable form of HA into knee joints and facial skin, at this time there are no human trials evaluating the oral benefits of hyaluronic acid.


You can spend hundreds—even thousands of dollars each year on topical moisturizers that help soften your skin. But if you want to truly give your skin the moisture it needs to maintain elasticity, strengthen collagen and minimize wrinkles and age spots, it’s a good idea to increase your levels of hyaluronic acid. Although it’s not proven, it makes sense that a natural hyaluronic acid supplement might help. And if maintaining healthy, beautiful skin is important to you, then it’s definitely worth a try. 

Editor's Note:

The natural health solutions described in this article are available through many on-line retailers including those listed below. By clicking these links you help support the important alternative health research we provide.

Visit NutriStand – The Nutrition Newstand from the Supplement Man for Science-Based Nutritional Supplements!

Visit International Antiaging-Systems for hard to find therapies. They specialize in Tomorrow's Treatments Today™.

Visit – a great way to find competitive deals on supplements offered by many different manufacturers.

Visit VitaE8 - The Ultimate Vitamin E – to learn more about the importance of full-spectrum vitamin E supplements.

This article is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.


  1. Stern R (August 2004). “Hyaluronan catabolism: a new metabolic pathway”. Eur J Cell Biol 83 (7): 317-25. PMID 15503855.

  2. Fraser JR, Laurent TC, Laurent UB. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med. 1997 Jul;242(1):27-33.

  3. Laurent TC, Laurent UB, Fraser JR. The structure and function of hyaluronan: An overview. Immunol Cell Biol. 1996 Apr;74(2).

  4. Meyer, L.J.M. & Stern, R. (1994) Age-dependent changes in hyaluronan in human skin. Journal of Investigative Dermatology, 102. 385-389.

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Sounds feasible but I am not happy about taking the supplement until I see some sound research results.  I would also like to know what the actual ingredients are - more man-made chemicals?

Been taking this product for a couple of months, to help my joints and to a small degree it has .. haven’t noticed and other benefits.

sounds good and truthful. I learned about HA in my biology class. will give it a try

Hydraulic acid is certainly a great supplement for the skin. The fact that wrinkles on the skin surface is primarily due to loss of collagen, the application of the ingredient does make sense.

How much HA do you need to take daily to get the full benifit and do you need to take collagen as well

“And if maintaining healthy, beautiful skin is important to you, then it’s definitely worth a try.”  Garbage science and even dumber statement/ conclusion.  This statement sounds like someone has some $$$ in it for them.  Read the NIH reports.  What could be scary is that HA is associated with metastasis of some forms of tumors. 

Want healthy and beautiful skin?  Choose your parents wisely, moderate sun exposure, don’t smoke and drink only in moderation, and spend your money on fruits, vegetables and a YMCA membership instead of all the junk supplements.

HA accumulation even figures in the Shar-Peis wrinkles.

High molecular weight HA may be of some benefit for joint repair, but the NIH literature survey casts doubts even on this conclusion.

iNot junk science. I have experimented extensively and anything that can hold moisture against the skin diff applications/formulas, could be amazing. I just got some powdered, can wait. I have resurfsced and gotten incredible results at home, I do not believe harsh chem peels are necessary/the answer. And no, Im sorry, I will not give my secrets away, but one thing, moisture plays a part in cummulative skin rejuv.

It is important however silica found abundantly in collagen is the most important factor in not only healthy skin but in overall health from hair to bones as well as a detoxifier. Silica allows you to absorb needed nutrients without proper amounts of silica in the body it dosnt matter what supplements you take. I am not a doctor but I do research and talk to people in this feild of study science is countinually discovering new information so do your research. Silica.

i have been blessed with good genes. i am 55 and only have slight wrinkles in my forehead which you cannot see unless i am in the sunlight.but i also eat right and take HGH to keep the body younger and from ageing so quickly. also exercise as well. but will consider taking Hyaluronic Acid and Collagen.

I am a 52 year old male. I have been taking 1,500 MG BioCell Collagen II (Chicken Collagen Type II) containing 150 MG Hyaluronic Acid twice a day for a few years now. I have very few really fine wrinkles in my facial skin, absolutley no sagging under my eyes. I can tell when I stop taking it because I get these little aches and pains I normally do not get when I do take it. I drink a lot of water to stay well hydrated. So bottom line here is that, for me at least, it has worked quite well for years. Keep in mind also the benifits it has for your joints as well. Have a great day !!

When I was 23 I had a severe case of acne. It left scars. Over the years I have tried a lot of things, even Hyaluronic acid made from chicken Or rooster or whatever. It didn’t work.  I started using Synthovial seven a year ago.. A dropper under the tongue every morning. My skin has soften and smoothed out scars & wrinkles. I look better today at 81 than I did when I was 50 yrs old Also helps my eyesight & joints.

Those who hawk nutritional supplements would make a stronger case for these products if they would stop attempting to suggest that “natural” substances can achieve the same results as cosmetic procedures.  Clearly, if they could, they would cost well in excess of their current price.
And the silly people who insist that a product “works” because they noticed a change in themselves that coincided with taking a given product ( doubtless along with 20 other substances….  the average consumer does not generally observe strict controls) do not help the case for nutriceuticals.  I do not want these products to be forbidden but the more manufacturers overstate their claims and the more unschooled lay “experts” expound the unfounded virtues of their personal experiments with products whose names they can’t spell or pronounce ( ” Hydraulic Acid”??) The sooner the FDA will have abundant reason to “save the public from themselves”....  I believe there is merit in “natural” products but manufacturers that overstate their benefits to a very gullible public are hastening the demise of our “free” market.

I don’t see anything that says taking this supplement will do the same as cosmetic procedures. That’s ridiculous to even think that. It simply states that the cosmetic procedures can be dangerous and that there is something else one can do, not that you will get the same results. Anyway, there was just a study completed demonstrating the safety and significant efficacy of hydrolyzed collagen and highly-bioavailable hyaluronic acid in improving a variety of aging-associated facial effects measured both qualitatively and quantitatively.  So there is scientific proof.

Hello, my name is Lilia
My question is, Can I use this acid chemical to elimanate bad pigmentation in my skin.

what is the max of Hyalurionic Acid can you take daily, so the body can function normally

I am a review reader, and I believe in testing product for myself. I believe my skin is effected from the inside out more then anything. I eat natural and organic as much as I can, but I also drink and smoke occasionally. I have a young face, but I am hitting 40 and have noticed less elasticin. I have only taken hyaluronic acid for 4 days. I see a difference already. I take vitamin supplements and use creams, but no real change. Maybe softer skin, but hyaluronic acid has given a new fuller structure to my face. I see my youthful face again.  My neck is the most noticeable. It was starting to look loose and hanging.  This was disturbing the most to me. It had now firmed up. I can’t stop looking at myself. This has never happened before. This is an amazing supplement. I will never stop taking it.

Hey mate, .This was an excellent post for such a hard subject to speak about. I look forward to seeing many much more excellent posts like this one. Thanks

Hello, I was watching tv one day & I saw a commercial about a facial filler. I think it was Jujuvederm or something similar in name. I looked it up on line to see what it consists of. I also ran across several other facial fillers. I noticed alot of the fillers last different amounts of time and had different ingredients. They talked about a calcium filler and something about Japan and how sweet potatos made you look younger because they eat alot of them in Japan and looked younger than other people. I noticed that the ingredients consisted of the foods that I never ate. I have started a high collagen diet which is helping me to see a more toner body after one workout. Whereas it took several months to see a change and the scale wouldnot change. I studied very hard about the HA. I also studied alot about glucosamine. Not sure if glucosamine is similar to glycosaminoglycan mentioned here, but I will check to make sure. Because I know my diet is lacking these nutrients and I liked the sound of the filler after I watched a video of the Dr performing one. It looked and sounded very healthy. I orded 60 HA tablets and they arrived today 6/27/2014. Searching on line to see how long before I notice the HA working, I ran across this page. Your comments have been helpful. The glucosamine works well after one pill but I donot like the ingredients. (for joint pain). Eating foods high in collagen and foods that have healthy fats and exercise will certainly work. Hope I can come back and say the HA has worked after the 30 days as well.

If you check out some of the facial fillers ingredients, (not Botox) but the fillers for laugh lines and lines of the forehead and around the mouth. The better fillers ARE HA and they last longer. Some are a certain form of calcium. I have not seen any that are not already in the body. You have to be smart and study for yourself. If HA does all this stuff with water, you have to drink alot of water, and then, on the other hand, I have read that not enough water causes eye bags and also not to drink water before you go to bed because it causes the facial swelling as well. Also not enough water causes facial swelling. You have to know your body. I am trying them by trial. I talked to a filler office $675 for two lines around the nose. I will see what this does. I need the HA in my diet any way. I eat alot of rosemary, this is supposed to prevent tumors.

I have been taking collagen and Hyaluronic acid for a week now, i have very oily acne skin, and since taking these….i can see my skin is looking smoother, younger and not as many spots! I am a smoker and even look like i have stopped , bearing in mind I haven’t taken them everyday either ( forgot for 2 days!) i feel its made a difference, I shall keep you all updated. I have had hyaluronic on my lips too, so hoping taking these will keep the filler longer :-) .

Hello, I stumbled upon this while doing some research on hyaluronic acid for a breakthrough product my company has just launched.  It uses patented Liquid Cone technology in a patch that delivers hyaluronic acid (99.9% active ingredient) and peptides (0.1%) directly into targeted lines and wrinkles for naturally smoother-looking skin—producing visible results in the majority of users from just one overnight use, and continuing to build over time. The difference is the technology – it is topical, not injectable.  You can literally fill a wrinkle overnight, no needle required!

Hello again! I first wrote while I held the bottle of HA in my hand back in July Its been 3 months now My face has certainly puffed a whole lot It scares me that my head looks so large to me but the laugh lines are still the same. It helped some other parts of my body. I think it has to be injected for the laugh lines. I noticed an afternoon nap helps my laugh lines more than exercise food and drugs. Thank You!

I would like to hear more from the person who wrote about Liquid Cone technology.  Please tell me more about it.  Thank you.

Hyaluronic Acid and Collagen is really good against various skin allergies. Last month I had a infection in my skin and my doctor suggested a cream and Web Based EMR  the main thing in that cream is Hyaluronic Acid.

I should say only that its awesome! The blog is informational and always produce amazing things.

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Isn’t there any other treatment that is not that risky? Because all these acid stuff are a bit spooky.
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i think there are also some side effects of using hyaluronic acid, could you pls provide a souce for that points? thanks
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