The latest peer-reviewed medical research further confirms: no one should be using HRT!
Conventional HRT increases risk of stroke
Research evaluating conventional hormone therapy and risk of stroke in postmenopausal women, published May 2011 in the British medical journal, Women’s Health, has further confirmed that conventional HRT, whether conjugated estrogens are used alone or in combination with a progestin, increases a woman’s risk for stroke. There is now a large amount of evidence demonstrating that HRT is associated with increased risk of stroke, in particular, ischemic stroke.”1
Conventional HRT increases risk of breast cancer
After the Women’s Health Initiative studies on HRT were terminated in 2002, several years earlier than originally planned because they revealed that HRT significantly increased risk of breast cancer, HRT use plummeted in many countries. Since then, a number of studies have reported a subsequent decrease in breast cancer incidence. The most recent reports come from Belgium and Germany.
Belgium had one of the highest incidences of breast cancer in Europe and also had a high rate of HRT use, with differences between different regions of the country, so researchers assessed breast cancer incidence and HRT sales per region.
A study looking at breast cancer incidence in Flanders, Brussels and Wallonia, especially among women 50-69 years of age, found that HRT use decreased by half from 2002 onwards. By 2003, breast cancer incidence had also decreased in all three regions, a trend that has continued.2
Another study looked at breast cancer incidence in the Belgian province of Limburg. Compared to 2002, in 2003 and 2004, the breast cancer incidence rate for women aged 50-69 years decreased significantly—a sudden drop that intercepted a markedly increasing trend until 2002. Between 2002 and 2006, sales of HRT dropped by 41%. Breast cancer incidence was found to be maximally (77%) related to HRT use in the previous year. The researchers’ concluded, “This suggests that HRT stimulates the growth of pre-existing, clinically latent tumors that may not otherwise become clinically apparent.”3
In Germany, just as in Belgium, the decrease in HRT use and decrease in breast cancer occurence were highly correlated. To quote the researchers, “A drastic change in age-incidence relationship in breast cancer has taken place…”4
In contrast, the drop in breast cancer incidence was not seen in younger (premenopausal) women, i.e., women who are not using HRT, but are highly likely to be using birth control pills, which contain progestins. It now appears that progestins, as well as conjugated equine estrogens, significantly increase a woman’s risk for breast cancer, among numerous other side effects. To learn more about why you should not be taking a progestin, read our articles on the following:
- Side Effects of the Progestins – the Drugs Used to Replace Human Progesterone in Conventional Hormone Replacement Therapy.
- Progestins – what other risks and side effects could they cause besides breast cancer, bone loss, cardiovascular disease and loss of libido?
Stay Young & Sexy with Bio-Identical Hormone Replacement: The Science Explained
This article summarizes key points presented in-depth in almost 500 pages in Stay Young & Sexy with Bio-Identical Hormone Replacement, the Science Explained by Jonathan V. Wright, MD, and. Lane Lenard, PhD. This book is the definitive resource on Bio-identical Hormone Replacement Therapy and fully explains why BHRT is the best option for women, not only to alleviate the discomforts of menopause, but to prevent the long-term negative health consequences of our aging-related decline in sex hormones.
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Renoux C, Suissa S. Hormone therapy administration in postmenopausal women and risk of stroke. Womens Health (Lond Engl). 2011 May;7(3):355-61.
Antoine C, Ameye L, Moreau M, et al. Evolution of breast cancer incidence in relation to hormone replacement therapy use in Belgium. Climacteric. 2011 Aug;14(4):464-71. Epub 2011 May 5.
Vankrunkelsven P, Kellen E, Lousbergh D, et al. Reduction in hormone replacement therapy use and declining breast cancer incidence in the Belgian province of Limburg. Breast Cancer Res Treat. 2009 Nov;118(2):425-32. Epub 2009 Feb 24.
Katalinic A, Rawal R. Decline in breast cancer incidence after decrease in utilisation of hormone replacement therapy. Breast Cancer Res Treat. 2008 Feb;107(3):427-30. Epub 2007 Apr 24.