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Natural GABA Can Help You Sleep!

by John Morgenthaler

More than 70 million Americans suffer from sleep disorders, and now researchers may have found a reason why.

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A new study examined GABA (gamma-aminobutyric acid) levels in a group of people who had a long history of sleep problems and found that their GABA levels were 30% below normal. This low level also contributes to anxiety and a poor mood.

GABA is the most important inhibitory neurotransmitter in the brain, and is essential to healthy relaxation and sleep. (Neurotransmitters are chemicals which relay, amplify and modulate signals between a neuron and another cell. Some neurotransmitters are described as "excitatory" or "inhibitory.")

Researchers at Brigham & Women's Hospital, Harvard Medical School evaluated eight men and eight women between the ages of 25-55, who were not on any sleep medications. They use proton magnetic resonance spectroscopy (1H-MRS) to determine GABA levels and the results were compared to a control group. The researchers concluded that as a whole, the groups’ sleep problems were clearly linked to low GABA levels. This preliminary study is very significant because it is the first one of its kind to show reduced levels of GABA in individuals with insomnia.1

A second recent double-blind, placebo controlled study at the UCLA School of Medicine, Los Angeles (released May 4, 09), followed 18 patients with sleep disorders who were given either a placebo or supplement containing GABA. Before they started the supplement, it took the treated group about 32 minutes to fall asleep. After taking the supplement, it only took about 19 minutes, on average. Before supplementation, the duration of their sleep was about 5 hours, and after supplementation it increased to about 6.83 hours. There was virtually no change in the placebo group.

The treated group experienced less morning grogginess, and a much easier time falling asleep, wakening and staying asleep for a longer period.2


Although these studies are preliminary, they point to low levels of GABA as being a contributor to sleep disorders. Based on these findings, along with personal accounts, raising GABA levels seems to have a significant impact on quality of sleep. 

Editor's Note:

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These articles are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.


  1. Winkelman JW, Buxton OM, Jensen JE, Benson KL, O'Connor SP, Wang W, Renshaw PF. Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS). Sleep. 2008 Nov 1;31(11):1499-506. 

  2. Shell W, Bullias D, Charuvastra E, May LA, Silver DS. A Randomized, Placebo-Controlled Trial of an Amino Acid Preparation on Timing and Quality of Sleep. Am J Ther. 2009 May 4. [Epub ahead of print]. 

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Your citations on the third study must be in error. A dosage range of 1.5 mg - 2.5 mg of GABA is far too small to produce any results whatsoever.  The amounts would have to be 1.5 - 2.5 GRAMS.

DC Yardley,

You are correct that the third study was cited in error.  This study actually referred to EVT 201, a positive allosteric GABA(A) receptor modulator. This section of the article has now been removed. We appreciate your pointing this out and apologize for any confusion.

One of the essentials of my stratum this semester is to arm in an My buddy directed me to the point to have instruction on where I can discover a salubrious author to do this. I am hoping you can aid.

I am one among the Americans who suffer from sleep disorder like insomnia. I have tried many medicines, even marijuana, but nothing has given permanent relief from the disorder. I would like to know if natural gaba is capable of helping me out. Thank you. ICD 10 Coding



  現在国内に主に五大革製品のシャネルコピー卸売市場があります:グッチ革製品白溝の革製品の市場、浙江義烏の革製品の卸売市場、遼寧南台の革製品グッチコピーの卸売市場、グッチ革製品の蓮の池の革製品の市場、広州のモクセイの監視塔の革製品の卸売市場、その中は、広州のモクセイの監視塔の革製品のシャネルコピー市場の規模で最大等級が最高で、全世界の最大の革製品の卸売市場で、5つが大型のジョルジオ アルマーニベルトコピー卸売市場に比べてを除いて、その他のはほぼすべて小型の卸売市場で、市場はあまりにも分散していて、グッチコピー品質、デザインと価格がまちまちです。  

我が国のバッグの製品は欧米国家のバッグの製品と品質のジョルジオ アルマーニベルトコピー上で大変な違いがあります。記者は知って、我が国のバッグのローエンドの市場は氾濫して、それらは散って各種の日用雑貨で城、露店に卸売りをして、80%の包む装飾はいくつか小工場、ミュウミュウ財布スーパーコピー小さい仕事場のする低級な製品のため、資金に不足するため、多い企業のハードウエアが施設とソフトウェアを生産して人材を研究開発する比較的薄弱で、つくりだす包む装飾がブランド、品質ほど悪くない、設計がない、個性がない、保障がない、あるもシャネル眼鏡新作のまた(まだ)使って大量にひどい原料があって、イメージを飾ることはできないだけではなくて、甚だしきに至っては人体に対して健康で有害で、都市人の生活のバッグ新作品質に対する追区を満足させることができなくて、特に長年来、プラダ店舗国内のバッグの企業は大部分グッチ財布レディースが輸出するのを主なにして、多くの企業が金融危機の後で国内販売するのに変わる時、ブランドがなくて、チームがなくて、ルートがなくて、革新、シャネル眼鏡新作自主ブランド、マーケティングのネットワークなどを設計する方面に明らかに見劣りがする国外で有名な、これは業界が比較的外部環境の揺れ動く影響を受けやすいのを招いて、そグッチ財布レディースの危険な状況に耐え抜く能力、利潤のレベルももすべて比較的比較的弱いです。


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