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Nattokinase—The Natural Blood Thinner
Helps reduce high blood pressure
Human volunteers with high blood pressure were given 30 grams of Natto extract (equivalent to 7 ounces of Natto food), orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure decreased on average from 173 to 154. Diastolic blood pressure decreased on average from 101 to 91. These impressive results represent about a 10.9 percent drop in systolic blood pressure and a 9.7 percent drop in diastolic blood pressure.569
A study of animals that were given Natto extract showed a significant drop in systolic blood pressure, also, from an average of 166 to 145 in just 2 hours, which further decreased to an average of 144 in 3 hours. This data represents an approximate 12.7 percent drop in systolic blood pressure within 2 hours.59
Restores blood circulation
This is one of the most dramatic case studies about the effects of Nattokinase. A 58-year-old man had a blood clot in the retina of his right eye that caused fluid build up and bleeding. He started losing his vision in that eye and was admitted to a university hospital, where researchers prescribed a three ounce dose of Natto to be taken before bed every night in order to get the benefit of Nattokinase.
The man’s bleeding completely stopped by the 10th day, and by the 20th day, his vision returned and he was released from the hospital. He continued to eat Natto twice a week. When he had a retinal angiogram two months later, it showed that the blood clot was completely gone.10
Excellent for periods of inactivity
This soy extract is considered extremely useful for those wanting a safe, non-drug, aspirin alternative for healthy blood flow. Over the past few years, medical professionals began alerting the public about the increasing evidence that long flights and car trips put people at risk for deep vein thrombosis (DVT)—a blood clot (thrombus) that develops in a deep vein, usually in the leg. DVT is more common in women than in men and in those over 40 years of age.
Deep vein thrombosis
DVT—blood clots inside veins found deep in extremities or body cavities—is a common disorder. A venous thrombus is a clump of blood cells, platelets, and fibrin (clot) which attaches to the inside walls of veins, can grow in size, and break off to travel downstream from the clot. If the clot stays localized, it can cause swelling and vein irritation. If part of it breaks off, it can cause blockage downstream, or become an embolus and result in a pulmonary embolus. In some instances, deep vein thrombosis may also contribute to other serious medical problems such as heart attack and stroke. Nattokinase can prevent DVT by not allowing the venous thrombus to develop.
How safe is Nattokinase?
As with any nutritional supplementation program, it is best to consult your physician before beginning a Nattokinase treatment program. Having said that, we can report that Nattokinase is safe for most people when used according to the recommended dosage. Some people should avoid Nattokinase. This includes people with bleeding disorders, such as hemophilia, or the group of diseases called hemorrhagic diathesis. Also, people with bleeding ulcers, bleeding hemorrhoids, or recent major trauma, or those who’ve had neurosurgery or a hemorrhagic stroke should not take Nattokinase. If you take heparin, Coumadin® or aspirin, use only under the close supervision of a medical doctor.
Healthy blood flow without the side effects of pharmaceuticals
Researchers have found that Nattokinase is four times more potent than plasmin, works more effectively than warfarin drugs, and doesn’t produce any side effects. On the other hand, the side effects associated with warfarin (such as Coumadin®) blood thinners are numerous and well documented. The short list includes:
- Hemorrhage - internal bleeding
- Abdominal pain and cramping
- Diarrhea
- Fatigue and lethargy
- Feeling cold and chills
- Liver damage
- Loss of hair
- Nausea
Conclusion
The traditional Japanese food Natto has been used safely for more than 1,000 years. The safety record of its potent fibrinolytic enzyme, Nattokinase, is based upon the long term traditional use of the food, and recent scientific studies.
Nattokinase has many benefits including its prolonged effects, cost effectiveness, and its ability to be used preventatively. It is a naturally occurring, food-based dietary supplement that has demonstrated stability in the gastrointestinal tract, as well as to changes in pH and temperature.
It would then seem prudent to add this effective natural product to your heart health preventive arsenal. Finally, a nutritional approach to reduce the health damaging, double-edged sword of plaque and plasma fibrins has arrived. Using a potent blend of oral EDTA chelation and vitamin K2 to reduce arterial plaque, and Nattokinase to prevent dangerous clots seems to make perfect sense.
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Editor's Note:
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This article is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.
References
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Prevent Heart Attack and Stroke with Potent Enzyme that Dissolves Deadly Blood Clots in Hours. Health Sciences Institute, March 2002.
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Heinrich, J. et al. Fibrinogen and factor VII in the prediction of coronary risk. Arterioscler Thromb 1994, 14:54-59.
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Sumi H. Interview With Doctor of Medicine Hiroyuki Sumi. Japan Bio Science Laboratory Co. Ltd.
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Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K. Dietary supplementation with fermented soybeans suppresses intimal thickening. Nutrition. 2003 Mar;19(3):261-4.
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Prevent Heart Attack and Stroke with Potent Enzyme that Dissolves Deadly Blood Clots in Hours. Health Sciences Institute, March 2002.
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Sumi, H. et al. “Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase.” Acta haematol 1990, 84: 139-43.
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Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S. Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 1995 Oct;18(10):1387-91.
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Suzuki Y, Kondo K, Matsumoto Y, Zhao BQ, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K. Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci. 2003 Jul 25;73(10):1289-98.
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Maruyama M, Sumi H. Effect of Natto Diet on Blood Pressure. JTTAS, 1995.
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Nishimura, K. et al. Natto diet was apparently effective in a case of incipient central retinal vein occlusion. Japan Rev Clin Ophthalmol 1994, 88:1381-85.