- A
- A
- A
Mitochondrial Theory of Aging Yields Startling Results
Mitochondrial Theory of AgingYields Startling Results
- Enjoy more vitality
- Prevent and arrest degenerative diseases
- Recharge your energy levels
- Pump up brain power
- Outsmart Father Time
- Safeguard your vision and hearing
Would you like to live to a ripe old age and maintain a sharp mind…good eyesight and hearing…and overall health?
-Sponsored Ads-
If your answer is "Yes" (and of course it is!), then continue reading to find out how!
It sounds like science fiction, but recently a team of scientists discovered one of the keys to what happens to the human body as it gets older—and how to delay and even reverse the aging process. We now know how and why cells deteriorate. And thanks to this discovery, we now have the power to age more slowly, live longer with better health, and even reverse some of the signs of aging!
Read our breakthrough report on how you can control how you age with a powerful, cutting-edge longevity supplement…that allows you to improve your odds of living longer and healthier.
How long do you want to live?
Over the centuries, there have been plenty of myths about the fountain of youth. Finally, we've got the groundbreaking research to take you where everyone has dreamed of…and few have been.
You've read about products that restore memory, skin elasticity, and agility. And, for the most part, they deliver at least some of their promises. But there's never been a special combination of ingredients that actually has been tested and proven in a lab to slow down aging and reverse damage that's already been done.
Now it really is possible to extend your life by decades…and live them in good health.
Based on published research of internationally renowned scientists, Dr. Bruce Ames and his team at the University of California, Berkeley, we now know that the combination of two unique antioxidant dietary supplements supercharges your cells' energy production in order to maximize memory, health, and longevity. This breakthrough research has even shown that the combination of these amazing nutrients has the potential of not only preventing aging, but of even reversing some signs of aging.
Cellular health and aging
One of the last unanswered questions in biology is how we age. And with Baby Boomers reaching their 50s, there are millions of people searching for the key to ward off wrinkles, aches and pains, and improve their odds of living longer.
Every once and while we read about centenarians like Elizabeth Pampo Israel, reported to be living in the Dominican Republic at the ripe old age of 127. Or Maud Farris-Luse, who recently died at age 115, and was recognized last year by the Guinness Book of World Records as the world's oldest living person.
While the average human life span over the past 2,000 years has risen from about 30 years to almost 80 years, the maximum potential life span of humans has remained near 120 years.
Although most of our peers probably won't make it to 120, recent exciting discoveries have brought us closer than ever to understanding the aging process and re-igniting the possibility that it really is possible to extend our life span and the life span of our children and grandchildren.
The Free Radical Theory of Aging - a new perspective
In the mid-1950s, Denham Harman, MD, PhD, developed the Free Radical Theory of Aging, which explains that cells eventually break down due to free radical attack resulting from oxidative stress. If you can imagine the body as a battlefield in which the cells are attacked by free radicals and damaged by the enemy, oxidation, then you have a pretty good idea of the scenario.
And if you could take a closer look at those besieged cells under a microscope, you'd see the molecules or atoms losing electrons. The molecules or atoms that accept these electrons are called oxidizing agents, and they have the potential to damage the cell's DNA, proteins and lipids. By-products of lipid peroxidation can result in cancer, Alzheimer's, arthritis, and numerous other diseases associated with aging. Over time, the cells die, and inevitably we age and die too.
Editor's Note:
The natural health solutions described in this article are available through many on-line retailers including those listed below. By clicking these links you help support the important alternative health research we provide.
Visit International Antiaging-Systems for hard to find therapies. They specialize in Tomorrow's Treatments Today™.
Visit www.amazon.com – a great way to find competitive deals on supplements offered by many different manufacturers.
Visit www.hfn-usa.com – when commitment to quality and freshness is important, this factory direct solution is preferred by many of our readers.
This article is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a physician before embarking on a dietary supplement program.
References
-
Cadenas E, Davies KJ. "Mitochondrial free radical generation, oxidative stress, and aging." Free Radic Biol Med 2000 Aug;29(3-4):222-30
-
Ebadi M. "Introduction. Oxidative stress in mitochondria disorders of aging." Biol Signals Recept 2001 Jan-Apr;10(1-2):5-13
-
Kowald A. "The mitochondrial theory of aging." Biol Signals Recept 2001 May-Aug;10(3-4):162-75
-
Allen JF, Allen CA. "A mitochondrial model for premature aging of somatically cloned mammals." IUBMB Life 1999 Oct;48(4):369-72
-
Van Remmen H, Richardson A. "Oxidative damage to mitochondria and aging." Exp Gerontol 2001 Jul;36(7):957-68
-
Wei YH, Lu CY, Wei CY, Ma YS, Lee HC. "Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system," Chin J Physiol 2001 Mar 31;44(1):1-11
-
Lino A, Boccia MM, Rusconi AC, Bellomonte L, Cocuroccia B. "Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration." Clin Ter. 1992 Jun;140(6):569-73
-
Sano M, Bell K, Cote L, Dooneief G, Lawton A, Legler L, Marder K, Naini A, Stern Y, Mayeux R. "Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease." Arch Neurol. 1992 Nov;49(11):1137-41
-
Bowman BA. "Acetyl-carnitine and Alzheimer's disease." Nutr Rev. 1992 May;50(5):142-4.
-
Postiglione A, Soricelli A, Cicerano U, Mansi L, De Chiara S, Gallotta G, Schettini G, Salvatore M. "Effect of acute administration of L-acetyl carnitine on cerebral blood flow in patients with chronic cerebral infarct." Pharmacol Res. 1991 Apr;23(3):241-6.
-
Rosadini G, Marenco S, Nobili F, Novellone G, Rodriguez G. "Acute effects of acetyl-L-carnitine on regional cerebral blood flow in patients with brain ischaemia." Int J Clin Pharmacol Res.1990;10(1-2):123-8.
-
Bella R, Biondi R, Raffaele R, Pennisi G. "Effect of acetyl-L-carnitine on geriatric patients suffering from dysthymic disorders." Int J Clin Pharmacol Res. 1990;10(6):355-60.
-
Packer L, Witt EH, Tritschler HJ. "alpha-Lipoic acid as a biological antioxidant." Free Radic Biol Med 1995 Aug;19(2):227-50
-
Kagan VE, Shvedova A, Serbinova E, Khan S, Swanson C, Powell R, Packer L."Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals." Biochem Pharmacol 1992 Oct 20;44(8):1637-49
-
Gregus Z, Stein AF, Varga F, Klaassen CD. "Effect of lipoic acid on biliary excretion of glutathione and metals." Toxicol Appl Pharmacol 1992 May;114(1):88-96
-
Lodge JK, Traber MG, Packer L. "Thiol chelation of Cu2+ by dihydrolipoic acid prevents human low density lipoprotein peroxidation." Free Radic Biol Med 1998 Aug;25(3):287-97
-
Murase K, Hattori A, Kohno M, Hayashi K. "Stimulation of nerve growth factor synthesis/secretion in mouse astroglial cells by coenzymes." Biochem Mol Biol Int 1993 Jul;30(4):615-21
-
Stoll S, Hartmann H, Cohen SA, Muller WE. "The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits."Pharmacol Biochem Behav 1993 Dec;46(4):799-805
-
Stoll S, Rostock A, Bartsch R, Korn E, Meichelbock A, Muller WE. "The potent free radical scavenger alpha-lipoic acid improves cognition in rodents." Acad Sci 1994 Jun 30;717:122-8
-
Muller U, Krieglstein J. "Prolonged pretreatment with alpha-lipoic acid protects cultured neurons against hypoxic, glutamate, or iron-induced injury." J Cereb Blood Flow Metab 1995 Jul;15(4):624-30
-
Nohl H, Gille L. "Evaluation of the antioxidant capacity of ubiquinol and dihydrolipoic acid." Z Naturforsch [C] 1998 Mar-Apr;53(3-4):250-3
-
Arivazhagan P, Juliet P, Panneerselvam C. "Effect of dl-alpha-lipoic acid on the status of lipid peroxidation and antioxidants in aged rats." Pharmacol Res 2000 Mar;41(3):299-303
-
Seidman MD, Khan MJ, Bai U, Shirwany N, Quirk WS. "Biologic activity of mitochondrial metabolites on aging and age-related hearing loss." Am J Otol 2000 Mar;21(2):161-7
-
Arivazhagan P, Panneerselvam C. "Effect of DL-alpha-lipoic acid on tissue nucleic acid contents in aged rats." Pharmacol Res2000 Sep;42(3):223-6
-
Arivazhagan P, Ramanathan K, Panneerselvam C. "Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats." Chem Biol Interact 2001 Nov 28;138(2):189-98
-
Zhang L, Xing GQ, Barker JL, Chang Y, Maric D, Ma W, Li BS, Rubinow DR. "Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway." Neurosci Lett 2001 Oct 26;312(3):125-8
-
Hagen TM, Liu J, Lykkesfeldt J, Ames BN, et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA. 2002 Feb 19;99(4):1870-5.
-
Liu J, Killilea DW, Ames BN. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci USA. 2002 Feb 19;99(4):1876-81.
-
Liu J, Head E, Gharib AM, Ames BN, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci USA. 2002 Feb 19;99(4):2356-61.